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Saruparib
go.drugbank.com/drugs/DB18982InvestigationalSaruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative
Zanidatamab zovodotin
go.drugbank.com/drugs/DB15472ExperimentalAccording to Zymeworks, "ZW49 (zanidatamab zovodotin) is a bispecific anti-HER2 ADC that is based on the same antibody framework as [ZW25] but armed with a cytotoxic payload." … [L8234] It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to existing HER2-targeted therapies
GSK2245035
go.drugbank.com/drugs/DB16076InvestigationalGSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
ZK-93423
go.drugbank.com/drugs/DB17063ExperimentalZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]
Supinoxin
go.drugbank.com/drugs/DB19010InvestigationalSupinoxin is under investigation in clinical trial NCT02003092 (RX-5902 Treatment of Subjects With Triple Negative Breast Cancer).
L-377202
go.drugbank.com/drugs/DB19022InvestigationalL-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).
Pyrrolidone
go.drugbank.com/drugs/DB19152ExperimentalPyrrolidone is under investigation in clinical trial NCT05444998 (Neoadjuvant Inituomab, Pyrrolidone and Nab-paclitaxel for Her2+breast Cancer).
Cannabidiolic acid
go.drugbank.com/drugs/DB19261InvestigationalCannabidiolic acid is under investigation in clinical trial NCT04103814 (Effect of Topical CBD Cream for Degenerative Hallux Disorders).
Ginkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
GS-6620
go.drugbank.com/drugs/DB15222InvestigationalGS-6620 is under investigation in clinical trial NCT01316237 (A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-6620 in Treatment Naïve Subjects With Chronic Hepatitis