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Plasmin (Human)
go.drugbank.com/drugs/DB22676InvestigationalThe enzyme plasmin causes clot lysis by cleaving fibrin, a clot component.[L53453]
Gamgertamig
go.drugbank.com/drugs/DB22765InvestigationalOM336 is under investigation in clinical trial NCT07083960 (OM336 in Autoimmune Cytopenias).
TRGFT-201
go.drugbank.com/drugs/DB23064ApprovedInvestigationalOrca-T (allogeneic regulatory T cell immunotherapy with HSPC and T cells-vldq) is a donor-derived allogeneic cell therapy used in matched-donor hematopoietic stem cell transplantation for adults with blood … , regulatory T cells (Tregs), and conventional T cells (Tcons) — administered as sequential infusions.
International brands: ORCA-TARX517
go.drugbank.com/drugs/DB23076InvestigationalARX517 is under investigation in clinical trial NCT04662580 (ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer).
Risvutatug rezetecan
go.drugbank.com/drugs/DB23560InvestigationalRisvutatug rezetecan (GSK5764227) is a novel investigational B7-H3-targeted antibody-drug conjugate. … It is under investigation in clinical trial NCT06885034 (A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers
Synonyms: HS-20093WNY0824
go.drugbank.com/drugs/DB23606Experimental[A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258] … WNY0824 is a preclinical small molecule drug being investigated for the treatment of Castration-Resistant Prostrate Cancer (CRPC).
Synonyms: PLK1/BRD4-IN-1Actinium Ac 225 Vipivotide tetraxetan
go.drugbank.com/drugs/DB23637InvestigationalActinium Ac 225 Vipivotide Tetraxetan is a small molecule drug. … Actinium Ac 225 Vipivotide Tetraxetan is under investigation in clinical trial NCT07150715 (Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy
Arlocabtagene autoleucel
go.drugbank.com/drugs/DB24024InvestigationalArlocabtagene Autoleucel is a biologic drug. … Arlocabtagene Autoleucel is under investigation in clinical trial NCT06297226 (Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or
Fiztasovimab
go.drugbank.com/drugs/DB24033InvestigationalFiztasovimab, also known as NPC‐21 and EV2038, is a monoclonal antibody. … [A278004, A278005] NPC-21 is under investigation in clinical trial NCT04225923 (A Study for Kidney Transplant Recipients at High-Risk of Cytomegalovirus Infection).
JNJ-64400141
go.drugbank.com/drugs/DB24373InvestigationalJNJ-64400141 is a biologic drug. … JNJ-64400141 is under investigation in clinical trial NCT05242432 (A Study of Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F (Ad26.RSV.preF)-Based Vaccine for Prevention of Respiratory
Synonyms: Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F