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Metformin C-11
go.drugbank.com/drugs/DB15181ExperimentalMetformin c-11 is under investigation in clinical trial NCT03122769 (Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography).
LP-2307
go.drugbank.com/drugs/DB17470ExperimentalLP-2307 is an investigational allogeneic large multivalent immunogen (LMI) vaccine developed by Avanir. It was investigated for melanoma.
TBI-223
go.drugbank.com/drugs/DB18911InvestigationalTBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Synonyms: CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL)-, METHYL ESTERRovadicitinib
go.drugbank.com/drugs/DB21747InvestigationalRovadicitinib is under investigation in clinical trials NCT06682169 and NCT06300320 for the treatment of Chronic Graft-versus-host Disease.
Escin
go.drugbank.com/drugs/DB15907Investigationalprognosis in massive cerebral infarction) and NCT05263167 (aimed at reducing edema after intracerebral hemorrhage). … Sodium aescinate is under investigation in clinical trials for its potential to treat cerebral conditions, including NCT04247659 (studying the relationship between asymmetric vascular sign of cortex and
Chimeric antigen receptor T-cells
go.drugbank.com/drugs/DB22146InvestigationalChimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian
AVR-RD-05
go.drugbank.com/drugs/DB18631ExperimentalIt is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII). … AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme.
Masofaniten
go.drugbank.com/drugs/DB21580InvestigationalMasofaniten is under investigation in clinical trial NCT06312670 (Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer). … Masofaniten is a small molecule drug.
PEP0101
go.drugbank.com/drugs/DB18572ExperimentalPEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.KBP-COVID-19
go.drugbank.com/drugs/DB15858InvestigationalAs of July 2020, KBP is conducting a Phase 1/2 clinical trial to evaluate the safety and immunogenicity of KBP-COVID-19 vaccine in healthy patients (NCT04473690). … Upon harvest, the antigens were purified, and these components underwent preclinical testing in animals.