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LV-SMENP Vaccine
go.drugbank.com/drugs/DB15804ExperimentalLV-SMENP-DC is a vaccine candidate being developed by Shenzhen Geno-Immune Medical Institute that comprises dendritic cells that are modified with lentiviral vector-expressing synthetic minigene which … This vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs). As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Nuvaxovid
go.drugbank.com/drugs/DB15810ApprovedInvestigational(Fractions A and C from _Quillaja saponaria_ extract). … Nuvaxovid (NVX-CoV2373) contains a recombinant mutant S protein that is codon-optimized for baculovirus-mediated expression in Sf9 cells derived from _Spodoptera frugiperda_ together with a Matrix-M adjuvant
Synonyms: SARS-CoV-2 rS, SARS-CoV-2 rS Nanoparticle VaccineV-SARS
go.drugbank.com/drugs/DB15812InvestigationalThis therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form. … Immunitor Inc., the sponsor, is currently testing this oral vaccine for immunogenicity in 20 healthy volunteers in a Phase 1 clinical trial (NCT04380532).
Lactobacillus acidophilus
go.drugbank.com/drugs/DB15823ApprovedInvestigationalMixtures: RisaQuad-2, GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETProducts: Flora QCiclonium bromide
go.drugbank.com/drugs/DB15827ExperimentalCategories: Heterocyclic Compounds, 1-RingRuscogenin
go.drugbank.com/drugs/DB15830InvestigationalMixtures: PROCTOLOG RECTAL KREM, 30 G, RECBUTIN % 5.8 + % 0.5 REKTAL KREM, 30 GBBV152
go.drugbank.com/drugs/DB15847Investigationalor a novel TLR7/8 agonist adsorbed gel. … The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel)
Synonyms: Whole-Virion Inactivated SARS-CoV-2 VaccineMVC-COV1901
go.drugbank.com/drugs/DB15854InvestigationalMVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. … As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210).
NasoVAX
go.drugbank.com/drugs/DB15859InvestigationalIt is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells[L16313]. … As of June 2020, NasoVAX is being evaluated in a Phase 2 clinical trial for safety and effectivness in preventing worsening symptoms in hospitalized COVID-19 patients (NCT04442230).
Inactivated SARS-Cov-2 Vaccine
go.drugbank.com/drugs/DB15862InvestigationalThis strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. … [A220158] Double-blind, randomized, placebo-controlled phase 1 (96 participants) and phase 2 (224 participants) were carried out in healthy adults between 18-59 years.