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Displaying results 9911 - 9920 of 10000 in total
  1. Drug

    Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

    go.drugbank.com/drugs/DB16443
    Investigational

    It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. … These promising results have secured a Phase I trial (NCT04530656) to evaluate the safety, efficacy, and immunogenicity in healthy Chinese participants.

  2. Drug

    (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide

    go.drugbank.com/drugs/DB06941
    Experimental

    (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide is a solid. This compound belongs to the phenylpiperazines.

    Synonyms: (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
  3. Drug

    OTL-102

    go.drugbank.com/drugs/DB18642
    Experimental

    It is being investigated for the treatment of X-linked chronic granulomatous disease.

  4. Drug

    Cinaciguat

    go.drugbank.com/drugs/DB16126
    Investigational

    Cinaciguat is under investigation in clinical trial NCT01067859 (A Phase Iib Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 ΜG/h, 10 ΜG/h) Given Intravenously to Patients

  5. Drug

    NGN-401

    go.drugbank.com/drugs/DB18594
    Investigational

    Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome. … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding

  6. Drug

    Devafidugene civaparvovec

    go.drugbank.com/drugs/DB16790
    Investigational

    Developed by Sangamo Therapeutics, Inc., devafidugene civaparvovec is being investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46716] … It uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme.

  7. Drug

    CP-39,332

    go.drugbank.com/drugs/DB09193
    Experimental

    CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). … It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency.

  8. Drug

    Zilpaterol

    go.drugbank.com/drugs/DB11479
    ExperimentalVet approved

    Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period to clear the drug from the tissues before slaughter. … Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of Merck & Co.

  9. Drug

    PHB-050

    go.drugbank.com/drugs/DB32061
    Experimental

    [L54988] It is under investigation for the treatment of multiple atopic diseases, including food allergies, asthma, and atopic dermatitis.[L54988] … PHB-050 is a novel, next-generation anti-IgE antibody designed to block IgE from binding to mast cells, while also rapidly reducing circulating IgE and inhibiting its production.

  10. Drug

    Zytron

    go.drugbank.com/drugs/DB11768
    ApprovedWithdrawn

    Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic).