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Inactivated SARS-Cov-2 Vaccine
go.drugbank.com/drugs/DB15862InvestigationalThis strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. … [A220158] Double-blind, randomized, placebo-controlled phase 1 (96 participants) and phase 2 (224 participants) were carried out in healthy adults between 18-59 years.
Probiorinse
go.drugbank.com/drugs/DB15870ExperimentalProbiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.
Human Amniotic Fluid
go.drugbank.com/drugs/DB15871InvestigationalHuman amniotic fluid is the liquid surrounding the human embryo and fetus. Physically, the fluid provides protection through cushioning. Chemically, the fluid provides protection through its inherent antibacterial properties. The fluid c...
Senna leaf
go.drugbank.com/drugs/DB15889ApprovedInvestigationalMixtures: Senna S, Multilax 1 CapSynonyms: Cassia senna l.CHO Cells Recombinant Vaccine
go.drugbank.com/drugs/DB15893ExperimentalThe vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability. … This vaccine candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and secreted by Chinese Hamster Ovary (CHO) cells[A219758].
Odesivimab
go.drugbank.com/drugs/DB15900ApprovedInvestigationalINMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320] … [A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection.
Chamazulene
go.drugbank.com/drugs/DB15931ExperimentalCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2D6 InhibitorsCloxyquin
go.drugbank.com/drugs/DB15933ExperimentalSynonyms: 5-Chloro-8-hydroxyquinolineCategories: Heterocyclic Compounds, 2-RingCasirivimab
go.drugbank.com/drugs/DB15941ApprovedInvestigational[L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … Casirivimab is a monoclonal antibody combined with [Imdevimab] in Regeneron's antibody cocktail known as REGN-COV2 for the treatment of COVID-19.
Piroctone
go.drugbank.com/drugs/DB15946InvestigationalRecently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma.[L34189] … Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages.
Categories: Heterocyclic Compounds, 1-Ring