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Escin
go.drugbank.com/drugs/DB15907Investigationalprognosis in massive cerebral infarction) and NCT05263167 (aimed at reducing edema after intracerebral hemorrhage). … Sodium aescinate is under investigation in clinical trials for its potential to treat cerebral conditions, including NCT04247659 (studying the relationship between asymmetric vascular sign of cortex and
Lumicitabine
go.drugbank.com/drugs/DB14808InvestigationalLumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and … Tablet) Compared to Their Respective Current Formulations, and to Assess the Effect of Food on the Pharmacokinetics of the 2 New Concept Formulations).
APR-2020
go.drugbank.com/drugs/DB18497InvestigationalAPR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
2-(5-fluoro-pentyl)-2-methyl-malonic-acid
go.drugbank.com/drugs/DB16029Investigational2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).
Fonadelpar
go.drugbank.com/drugs/DB16169InvestigationalFonadelpar is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease).
Chimeric antigen receptor T-cells
go.drugbank.com/drugs/DB22146InvestigationalChimeric Antigen Receptor T-cells is under investigation in clinical trial NCT05225363 (Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian
PNT001
go.drugbank.com/drugs/DB18375InvestigationalPNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.
Mavelertinib
go.drugbank.com/drugs/DB16228InvestigationalMavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
DCVax-L
go.drugbank.com/drugs/DB17580InvestigationalDCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded _in vitro_ with autologous tumour lysate.
BTRX-246040
go.drugbank.com/drugs/DB16048InvestigationalBTRX-246040 is under investigation in clinical trial NCT03193398 (BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder).