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Displaying results 9941 - 9950 of 10000 in total
  1. Drug

    Ginisortamab

    go.drugbank.com/drugs/DB18863
    Investigational

    Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced

  2. Drug

    Depulfavirine

    go.drugbank.com/drugs/DB18890
    Investigational

    Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

    Synonyms: 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
  3. Drug

    Etofibrate

    go.drugbank.com/drugs/DB08983
    Experimental

    These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. … Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin.

  4. Drug

    Sulfatide

    go.drugbank.com/drugs/DB04780
    Experimental

    Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.

  5. Drug

    Isoquercetin

    go.drugbank.com/drugs/DB12665
    Investigational

    VTE in Colorectal Cancer, among others. … Isoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein

  6. Drug

    Cephalothin Group

    go.drugbank.com/drugs/DB03450
    Experimental

    These are organic compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atom in ring positions 1 and 3 respectively, as well as two double bonds. … Cephalothin group is a solid. This compound belongs to the 1,3-thiazines.

  7. Drug

    SBT-100

    go.drugbank.com/drugs/DB17215
    Experimental

    SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). … It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]

  8. Drug

    TMC-649128

    go.drugbank.com/drugs/DB15152
    Investigational

    TMC-649128 is under investigation in clinical trial NCT01391117 (TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics

  9. Drug

    BBV152

    go.drugbank.com/drugs/DB15847
    Investigational

    Thus, as of July 2020, BBV152 is in Phase 1/2 clinical trials assessing safety and immunogenicity in humans (NCT04471519). … Animal studies in mice, rats, and rabbits reported BBV152 immunogenicity at two separate antigen concentrations with both types of adjuvants.

  10. Drug

    JNJ-28330835

    go.drugbank.com/drugs/DB13936
    Experimental

    A selective androgen receptor modulator with minimal prostate hypertrophic activity, enhances lean body mass in male rats and stimulates sexual behavior in female rats.