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Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine
go.drugbank.com/drugs/DB15813InvestigationalAs of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these engineered minigenes to express viral proteins
Deuremidevir
go.drugbank.com/drugs/DB26606InvestigationalDeuremidevir is under investigation in clinical trial NCT06328400 (A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Deuremidevir Hydrobromide for Suspension). … Deuremidevir is a small molecule drug.
SR-9011
go.drugbank.com/drugs/DB14014ExperimentalSR-9011 is a REV-ERB agonist. … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues
Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Salacetamide
go.drugbank.com/drugs/DB20217InvestigationalSalacetamide is under investigation in clinical trial NCT00220285 (Study for Evaluation of Efficacy and Safety of SH L 749 to Indolent B-cell Non-Hodgkin's Lymphoma). … Salacetamide is a small molecule drug.
PNT001
go.drugbank.com/drugs/DB18375InvestigationalPNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.
Mavelertinib
go.drugbank.com/drugs/DB16228InvestigationalMavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
DCVax-L
go.drugbank.com/drugs/DB17580InvestigationalDCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded _in vitro_ with autologous tumour lysate.
BTRX-246040
go.drugbank.com/drugs/DB16048InvestigationalBTRX-246040 is under investigation in clinical trial NCT03193398 (BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder).
ORM-13070 C-11
go.drugbank.com/drugs/DB15324InvestigationalORM-13070 C-11 is under investigation in clinical trial NCT00735774 (Suitability of 11C-ORM-13070 as a PET Tracer).
Artemin
go.drugbank.com/drugs/DB15438InvestigationalArtemin is under investigation in clinical trial NCT01842126 (Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin)).