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Displaying results 9981 - 9990 of 10000 in total
  1. Drug

    Xiliertinib

    go.drugbank.com/drugs/DB21453
    Investigational

    Xiliertinib is under investigation in clinical trial NCT02601274 (Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor). Xiliertinib has a monoisotopic molecular weight of 442.21 Da. … Xiliertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor.

  2. Drug

    Paltimatrectinib

    go.drugbank.com/drugs/DB21588
    Investigational

    Paltimatrectinib is under investigation in clinical trial NCT04901806 (Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors). … Paltimatrectinib is a small molecule drug. The usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.

  3. Drug

    Calcitonin porcine

    go.drugbank.com/drugs/DB13189
    Experimental

    Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in Britain was porcine calcitonin (brand name Calcitare). … Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations.

  4. Drug

    Dexfadrostat

    go.drugbank.com/drugs/DB21746
    Investigational

    Dexfadrostat is under investigation in clinical trial NCT04007406 (DP13 - a Phase II Study in Patients With Primary Aldosteronism).

    Synonyms: Fadrozole, (r)-
  5. Drug

    Chlorproguanil

    go.drugbank.com/drugs/DB12314
    Investigational

    Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide.

  6. Drug

    Icenticaftor

    go.drugbank.com/drugs/DB21466
    Investigational

    Icenticaftor is under investigation in clinical trial NCT04396366 (Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis). … The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

  7. Drug

    Fipravirimat

    go.drugbank.com/drugs/DB21578
    Investigational

    Fipravirimat is under investigation in clinical trial NCT04493216 (A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults). … Fipravirimat is a small molecule drug. The usage of the INN stem '-virimat' in the name indicates that Fipravirimat is a antiviral, disruptor of viral maturation.

  8. Drug

    Foselutoclax

    go.drugbank.com/drugs/DB21663
    Investigational

    Foselutoclax is a small molecule drug. The usage of the INN stem '-toclax' in the name indicates that Foselutoclax is a B-cell lymphoma 2 (Bcl-2) inhibitor. … Foselutoclax is under investigation in clinical trial NCT06011798 (Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)).

  9. Drug

    Conteltinib

    go.drugbank.com/drugs/DB21262
    Investigational

    Conteltinib is under investigation in clinical trial NCT06970132 (Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation). … Conteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor.

  10. Drug

    IK-930

    go.drugbank.com/drugs/DB18149
    Investigational

    IK-930 is an oral, paralog-selective TEAD inhibitor.