Chlorproguanil

DB12314InvestigationalSmall molecule

Chlorproguanil has been used in trials studying the treatment of MALARIA. It is a dichloro-derivative of chloroguanide.

Chemical structure of Chlorproguanil
Formula / weight
C11H15Cl2N5 · 288.18 g/mol (avg)

Resolves to

Compound
UNII8O3249M729CAS537-21-3ChEMBLCHEMBL1213553ChEBI135192PubChem9571037
Clinical / RWD
PharmGKBPA165857067
Structure
InChIKeyISZNZKHCRKXXAU-UHFFFAOYSA-NSMILESCC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C(Cl)=C1
Targets
Q9HBH1PDF

What you can answer from here — as of September 16, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
68Drug interactionsStructured to mechanism, not free text
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11Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Chlorproguanil, and which of those have an active Phase 3 trial?

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