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  1. Target

    Uric acid degradation bifunctional protein

    go.drugbank.com/bio_entities/BE0001313
    TargetBacillus sp. (strain TB-90)

    steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin

  2. Target

    Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

    go.drugbank.com/bio_entities/BE0023607
    EnzymeHumans

    Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin, a step in the uric acid degradation pathway following urate oxidation (By similarity

  3. Target

    Allantoate amidohydrolase

    go.drugbank.com/bio_entities/BE0001602
    TargetEscherichia coli (strain K12)

    Involved in the anaerobic nitrogen utilization via the assimilation of allantoin (PubMed:10601204, PubMed:20038185).

  4. Target

    L-hydantoinase

    go.drugbank.com/bio_entities/BE0001775
    TargetArthrobacter aurescens

    Rather more predominant for the cleavage of aryl- than for alkyl-hydantoin derivatives. The stereoselectivity of this enzyme depends on the substrate used for bioconversion: strictly L-selective for the cleavage of D,L-5-indolylmethylhyd...

    Function: allantoinase activity