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Antihemophilic factor, human recombinant
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Antihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalAntihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential … Other drug products with similar structure and function to Antihemophilic factor human include [DB13999], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced
Synonyms: Antihemophilic factor human, Antihemophilic factor, humanMixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalAntihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated … Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product _Adynovate_ [FDA label].
Categories: Human Antihemophilic Factors, Recombinant ProteinsSynonyms: Antihemophilic Factor (Recombinant), PEGylated, antihemophilic factor (recombinant), PEGylated-auclRurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigationalRurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. … [L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant factor VIII produced by recombinant DNA technology from a Chinese hamster ovary cell line.
Synonyms: Antihemophilic factor, pegylated (mw 20000) human sequence recombinant, Antihemophilic factor (recombinant), pegylated (20 kda)Categories: Recombinant Proteins, Factor VIIIMoroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedTreatment has drastically improved since the 1960s when Factor VIII protein was primarily purified from human plasma, rather than being produced through recombinant DNA technology. … is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived
Synonyms: Antihemphilic factor, recombinant human B-domain deleted, Human factor VIII, recombinant B-domain deletedCategories: Recombinant Proteins, Biological FactorsEfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalEfmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII … VIII, but does not contain the B-domain, which has no known biological function, and [DB13192], which is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits.
Synonyms: Antihemophilic factor (recombinant, FC fusion protein), Antihemophilic Factor (Recombinant BDD), FC Fusion ProteinCategories: Human Antihemophilic FactorsVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigational[L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic vWF products are also available as a combination product with [antihemophilic factor human] … The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis.
Mixtures: von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Categories: von Willebrand factor and coagulation factor VIII in combination, von Willebrand FactorSusoctocog alfa
go.drugbank.com/drugs/DB11606ApprovedInvestigationalThe recombinant porcine sequence allows less susceptibility to inactivation by circulating human factor VIII antibodies. … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein.
Categories: Blood Coagulation FactorsSynonyms: Antihemophilic factor (recombinant) porcine sequence, ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCEEfanesoctocog alfa
go.drugbank.com/drugs/DB16662ApprovedInvestigationalEfanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding … [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ceiling to which other forms of recombinant FVIII are subjected due to their association with von Willebrand
Synonyms: Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtlCategories: Recombinant Proteins, Recombinant Fusion ProteinsTuroctocog alfa pegol
go.drugbank.com/drugs/DB14738ApprovedInvestigationalFundamentally, the N8-GP moiety is identical to [turoctocog alfa], a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the … Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human or animal-derived materials [F3685].
Categories: Recombinant Proteins, Factor VIIISynonyms: Antihemophilic factor (recombinant), glycopegylated-exei