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Displaying results 1 - 10 of 251 in total
  1. Target

    Potassium

    go.drugbank.com/bio_entities/BE0004816
    TargetHumans

  2. Target

    Mitochondrial potassium channel

    go.drugbank.com/bio_entities/BE0009966
    TargetHumans

    Pore-forming subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)) (PubMed:31435016). … An increase in ATP intracellular levels closes the channel, inhibiting K(+) transport, whereas a decrease in ATP levels enhances K(+) uptake in the mitochondrial matrix.

    Polypeptides: Mitochondrial potassium channelFunction: mitochondrial ATP-gated potassium channel activity
  3. Target

    Hydrogen potassium ATPase

    go.drugbank.com/bio_entities/BE0009378
    TransporterTargetHumans

    Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity). … Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (By similarity

    Polypeptides: Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta
  4. Target

    Inward rectifier potassium channel

    go.drugbank.com/bio_entities/BE0003903
    TargetBurkholderia xenovorans (strain LB400)

    Polypeptides: Inward rectifier potassium channelSynonyms: Putative inward rectifier potassium channel
  5. Target

    Calcium-activated potassium channel

    go.drugbank.com/bio_entities/BE0004906
    TargetHumans

    Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. … Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

    Polypeptides: Calcium-activated potassium channel subunit alpha-1, Calcium-activated potassium channel subunit beta-1Synonyms: Calcium-activated potassium channel subunit beta, Calcium-activated potassium channel, subfamily M subunit alpha-1
  6. Target

    ATP-sensitive potassium channel

    go.drugbank.com/bio_entities/BE0004905
    TargetHumans

    Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. … Inward rectifier potassium channel that forms the pore of ATP-sensitive potassium channels (KATP), regulating potassium permeability as a function of cytoplasmic ATP and ADP concentrations in many different

    Polypeptides: ATP-sensitive inward rectifier potassium channel 1, ATP-sensitive inward rectifier potassium channel 10Synonyms: ATP-regulated potassium channel ROM-K, Potassium channel, inwardly rectifying subfamily J member 1
  7. Target

    Inward rectifier potassium channel

    go.drugbank.com/bio_entities/BE0009631
    TargetHumans

    Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. … Can be blocked by extracellular barium and cesium

    Polypeptides: Inward rectifier potassium channel 2, Inward rectifier potassium channel 4Synonyms: Cardiac inward rectifier potassium channel, Potassium channel, inwardly rectifying subfamily J member 12
  8. Target

    Voltage-gated Potassium Channels

    go.drugbank.com/bio_entities/BE0009847
    Target

    Regulatory subunit of the voltage-gated potassium (Kv) Shaker channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits (PubMed:17156368, PubMed:17540341 … Regulatory subunit of the voltage-gated potassium (Kv) Shaker channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits (PubMed:11825900, PubMed:7649300)

    Polypeptides: A-type voltage-gated potassium channel KCND1, A-type voltage-gated potassium channel KCND2Synonyms: Shal-type potassium channel KCND1, Minimal potassium channel
  9. Target

    Sodium/Potassium Transporting ATPase

    go.drugbank.com/bio_entities/BE0010055
    TargetTransporterHumans

    This process maintains essential Na(+) and K(+) gradients for membrane potential and cellular function. … Plays an essential for sperm motility, capacitation, and male fertility by maintaining ionic gradients required for flagellar function and signaling (By similarity)

    Polypeptides: Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-2Synonyms: Sodium/potassium-dependent ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-2
  10. Target

    pH-gated potassium channel KcsA

    go.drugbank.com/bio_entities/BE0003864
    TargetStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

    Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel.

    Polypeptides: pH-gated potassium channel KcsA