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Pazopanib Action Pathway

Pazopanib is an antineoplastic agent utilized for treating advanced renal cell cancer and advanced soft tissue sarcoma in patients who have undergone prior chemotherapy. … targeting vascular endothelial growth factor receptors (VEGFR-1, -2, -3), platelet-derived growth factor receptors (PDGFR-alpha, PDGFR-beta), and c-kit, which are integral to the angiogenesis pathway, pazopanib