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Ripretinib Action Pathway
smpdb.ca/view/SMP0126912Drug actionRipretinib is a kinase inhibitor primarily used to treat advanced gastrointestinal stromal tumor (GIST) that has not responded well to other kinase inhibitors like sunitinib and imatinib. … Ripretinib's mechanism of action involves inhibiting protein kinases, including both wild type and mutant forms of platelet-derived growth factor receptor A (PDGFRA) and KIT, which are implicated in the
Ripretinib Predicted Metabolism Pathway
smpdb.ca/view/SMP0174724MetabolicMetabolites of Ripretinib are predicted with biotransformer.