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Sunitinib Action Pathway
smpdb.ca/view/SMP0126868Drug actionSunitinib also affects RET, CSF-1R, and flt3 RTKs. … The primary metabolite mirrors sunitinib's potency in relevant assays.
Regorafenib Action Pathway
smpdb.ca/view/SMP0126907Drug actionIt is also used for patients with locally advanced, unresectable, or metastatic gastrointestinal stromal tumors who have been previously treated with imatinib mesylate and sunitinib malate.