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Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzym...
Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg contains the same distribution of IgG antibody subclasses as is found in the general human population. … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation.
Synonyms: Human IGG, Human gammaglobulinCategories: Human Immunoglobulin GPegvorhyaluronidase alfa
go.drugbank.com/drugs/DB14912InvestigationalPegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Synonyms: PEGylated recombinant human hyaluronidase PH20, HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR-(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORMBerahyaluronidase alfa
go.drugbank.com/drugs/DB22790ApprovedInvestigationalBerahyaluronidase alfa is a recombinant variant of human hyaluronidase designed to enhance dispersion and permeation of subcutaneously co-administered drugs.
Categories: Hyaluronidases, Recombinant ProteinsEfgartigimod alfa
go.drugbank.com/drugs/DB15270ApprovedInvestigational[L43190] A formulation for subcutaneous use that combines efgartigimod alfa and hyaluronidase was later approved for the treatment of patients with chronic inflammatory demyelinating polyneuropathy (CIDP
Categories: Human Immunoglobulin GSecondary humoral immunodeficiency
go.drugbank.com/conditions/DBCOND0150607Advanced Esophageal Adenocarcinoma
go.drugbank.com/conditions/DBCOND0129586Advanced Gastric Carcinoma
go.drugbank.com/conditions/DBCOND0032323Completely resected Stage IIB melanoma
go.drugbank.com/conditions/DBCOND0160974Completely resected Stage III melanoma
go.drugbank.com/conditions/DBCOND0160976