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DrugBest match

Thiotepa

go.drugbank.com/drugs/DB04572
ApprovedInvestigational

N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. It is also used as condi...

  1. Pathway

    Thiotepa Drug Metabolism

    smpdb.ca/view/SMP0130684
    Metabolic

    Thiotepa passes through the liver and is then excreted from the body mainly through the kidney. … Thiotepa is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Thiotepa
  2. Indication

    Breast Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0029215
    Drugs: Thiotepa
  3. Indication

    Papillary transitional cell carcinoma of bladder

    go.drugbank.com/conditions/DBCOND0089350
    Drugs: Epirubicin · Thiotepa
  4. Indication

    Adenocarcinoma of the Ovaries

    go.drugbank.com/conditions/DBCOND0038690
    Drugs: Cyclophosphamide · Thiotepa
  5. Indication

    Malignant effusion

    go.drugbank.com/conditions/DBCOND0024630
    Drugs: Mechlorethamine · Thiotepa