Search

Displaying results 1 - 10 of 7463 in total
  1. Drug

    Chloroquine

    go.drugbank.com/drugs/DB00608
    ApprovedInvestigationalVet approved

    Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. … [A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020.

    Synonyms: Chloroquine, ChloraquineSalts: Chloroquine sulfate, Chloroquine phosphate
  2. Drug

    Ezurpimtrostat

    go.drugbank.com/drugs/DB16458
    Investigational

    Synonyms: Chloroquine analogCategories: Experimental Unapproved Treatments for COVID-19
  3. Drug

    Cipaglucosidase alfa

    go.drugbank.com/drugs/DB16708
    ApprovedInvestigational

    [A232955, A232960] In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease … [A232955, A232960] In September 2023, the FDA also approved cipaglucosidase alfa for similar indications.[L49241]

    Synonyms: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate
  4. Drug

    Fecal microbiota

    go.drugbank.com/drugs/DB17743
    ApprovedInvestigational

    given an antibacterial treatment for recurrent CDI. … For this type of therapy to be efficient, qualified donors must be selected.

    Synonyms: Fecal Microbiota for Transplant
  5. Drug

    MM-111

    go.drugbank.com/drugs/DB17983
    Investigational

    MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.

    Synonyms: Antibody bispecific for erbb2 and erbb3
  6. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic

    Synonyms: Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid sequence
  7. Drug

    BI-836858

    go.drugbank.com/drugs/DB17267
    Investigational

    Synonyms: Fully Human Igg1 Antibody Specific For Cd33
  8. Drug

    Eluvixtamab

    go.drugbank.com/drugs/DB17252
    Investigational

    Synonyms: A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy
  9. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    autologous T cell immunotherapy product consisting of CD4 and CD8 positive T cells transduced with a self-inactivating lentiviral vector (LV) expressing an affinity-enhanced T cell receptor (TCR) specific for … [L51114, L51119] Afamitresgene autoleucel is first prepared from the patient’s peripheral blood mononuclear cells (PBMCs), which are enriched for T cells and are then transduced with a replication-incompetent

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  10. Drug

    Col-Treg

    go.drugbank.com/drugs/DB18451
    Experimental

    Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.[A261635]

    Synonyms: Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen