Mutations in SDHC cause autosomal dominant paraganglioma, type 3.
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Niemann S, Muller U
Mutations in SDHC cause autosomal dominant paraganglioma, type 3.
Nat Genet. 2000 Nov;26(3):268-70.
- PubMed ID
- 11062460 [ View in PubMed]
- Abstract
Nonchromaffin paragangliomas (PGLs) are usually benign, neural-crest-derived, slow-growing tumours of parasympathetic ganglia. Between 10% and 50% of cases are familial and are transmitted as autosomal dominant traits with incomplete and age-dependent penetrance.