Summary of clinical experiences with tamsulosin for the treatment of benign prostatic hyperplasia.

Article Details

Citation

Lowe FC

Summary of clinical experiences with tamsulosin for the treatment of benign prostatic hyperplasia.

Rev Urol. 2005;7 Suppl 4:S13-21.

PubMed ID
16986050 [ View in PubMed
]
Abstract

Tamsulosin, a uroselective alpha(1A)-adrenergic-receptor antagonist, has been shown to improve lower urinary tract symptoms associated with benign prostatic hyperplasia. It has a better side effect profile than earlier alpha-adrenergic-receptor antagonists, which were initially developed as antihypertensive agents. Clinical trials of 1 year or longer with tamsulosin show high tolerability for the 0.4 mg dose and no significant interaction with other antihypertensive medications.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
TamsulosinAlpha-1D adrenergic receptorProteinHumans
Unknown
Antagonist
Details