Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis.
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Kang LW, Gabelli SB, Cunningham JE, O'Handley SF, Amzel LM
Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis.
Structure. 2003 Aug;11(8):1015-23.
- PubMed ID
- 12906832 [ View in PubMed]
- Abstract
Nudix hydrolases are a family of proteins that contain the characteristic sequence GX(5)EX(7)REUXEEXG(I/L/V), the Nudix box. They catalyze the hydrolysis of a variety of nucleoside diphosphate derivatives such as ADP-ribose, Ap(n)A (3