Insulin-like growth factor II receptor as a multifunctional binding protein.
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Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, Rutter WJ
Insulin-like growth factor II receptor as a multifunctional binding protein.
Nature. 1987 Sep 24-30;329(6137):301-7.
- PubMed ID
- 2957598 [ View in PubMed]
- Abstract
The primary structure of human insulin-like growth factor II receptor, predicted from the complementary DNA sequence, reveals a transmembrane receptor molecule with a large extracellular domain made up of fifteen repeat sequences and a small region homologous to the collagen-binding domain of fibronectin. The structural and biochemical features of the IGF-II receptor appear identical to those of the cation-independent mannose-6-phosphate receptor.