Description of fourteen new DRB alleles found in a stem cell donor registry.

Article Details

Citation

Tang TF, Lin YS, Robbins FM, Li L, Sintasath D, Coquillard G, Huang A, Heine U, Ng J, Hartzman RJ, Hurley CK

Description of fourteen new DRB alleles found in a stem cell donor registry.

Tissue Antigens. 2002 Jan;59(1):63-5. doi: 10.1034/j.1399-0039.2002.590115.x.

PubMed ID
11972885 [ View in PubMed
]
Abstract

Fourteen DRB alleles, DRB1*0705, DRB1*11014, DRB1*1134, DRB1*1136, DRB1*1141, DRB1*1335, DRB1*1337, DRB1*1338, DRB1*1342, DRB1*1343, DRB1*1349, DRB1*1510, DRB3*0105, and DRB5*0103, are described. Among them, eleven are variants which differ by only one nucleotide from previously described alleles, including one silent variant (DRB1*11014). Alleles, DRB1*0705, DRB1*1335 and DRB3*0105, display unique sequence motifs that have never been observed in DRB alleles.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
HLA class II histocompatibility antigen, DR beta 3 chainP79483Details