Dihydroxybenzoylserine--a siderophore for E. coli.

Article Details

Citation

Hantke K

Dihydroxybenzoylserine--a siderophore for E. coli.

FEMS Microbiol Lett. 1990 Jan 15;55(1-2):5-8. doi: 10.1016/0378-1097(90)90158-m.

PubMed ID
2139424 [ View in PubMed
]
Abstract

Dihydroxybenzoylserine, the breakdown product of enterochelin, was able to stimulate growth of Escherichia coli under iron limiting conditions by acting as a siderophore. The dihydroxybenzoylserine-iron complex was taken up via the outer membrane receptor proteins Fiu, FepA and to a minor extent via Cir. Transport of Fe3(+)-dihydroxybenzoylserine across the cytoplasmic membrane was only dependent on genes from the fep region. In addition, it was shown that dihydroxybenzoate was taken up via Fiu and Cir and less efficiently by FepA.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Catecholate siderophore receptor FiuP75780Details