Heterogeneity in human soluble guanylate cyclase due to alternative splicing.
Article Details
- CitationCopy to clipboard
Chhajlani V, Frandberg PA, Ahlner J, Axelsson KL, Wikberg JE
Heterogeneity in human soluble guanylate cyclase due to alternative splicing.
FEBS Lett. 1991 Sep 23;290(1-2):157-8. doi: 10.1016/0014-5793(91)81248-7.
- PubMed ID
- 1680753 [ View in PubMed]
- Abstract
Two forms of the smaller subunit of the human soluble guanylate cyclase enzyme have been cloned by using PCR. One of the clones (HSGC-1) is identical to bovine and rat lung smaller subunit cyclase. However, the other (HSGC-2) is lacking 33 amino acids. Comparison of its sequence with published partial genomic sequences of bovine guanylate cyclase indicates that HSGC-2 is formed due to alternative splicing.