Aminoglycosides

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Block M, Blanchard DL

Aminoglycosides

.

PubMed ID

31082149 [ View in PubMed

]

Abstract

While aminoglycosides are an older class of medication, they continue to be clinically valuable. Aminoglycosides have a broad spectrum of activity covering aerobic organisms, including gram-negative bacteria and mycobacteria. There are several drugs within the aminoglycoside class, including gentamicin, tobramycin, amikacin, neomycin, plazomicin, and streptomycin, and FDA approved indications vary between the for these individual aminoglycosides. This activity reviews the indications, contraindications, mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent to members of the interprofessional team who wish to prescribe aminoglycosides.

DrugBank Data that Cites this Article

Drugs

Streptomycin

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Streptomycin	16S ribosomal RNA	Nucleotide	Enteric bacteria and other eubacteria	Yes	Inhibitor	Details