Effects of thyroid dysfunction on lipid profile.

Article Details

Citation

Copy to clipboard

Rizos CV, Elisaf MS, Liberopoulos EN

Effects of thyroid dysfunction on lipid profile.

Open Cardiovasc Med J. 2011;5:76-84. doi: 10.2174/1874192401105010076. Epub 2011 Feb 24.

PubMed ID

21660244 [ View in PubMed

]

Abstract

Thyroid dysfunction has a great impact on lipids as well as a number of other cardiovascular risk factors. Hypothyroidism is relatively common and is associated with an unfavorable effect on lipids. Substitution therapy is beneficial for patients with overt hypothyroidism, improving lipid profile. However, whether subclinical hypothyroidism should be treated or not is a matter of debate. On the other hand, hyperthyroidism can be associated with acquired hypocholesterolemia or unexplained improvement of lipid profile. Overall, thyroid dysfunction should be taken into account when evaluating and treating dyslipidemic patients.

DrugBank Data that Cites this Article

Pharmaco-metabolomics

Drug	Drug Groups	Metabolite	Change	Description
Levothyroxine	Approved	Total cholesterol	decreased	Levothyroxine decreases the level of Total cholesterol in the blood
Levothyroxine	Approved	LDL cholesterol	decreased	Levothyroxine decreases the level of LDL cholesterol in the blood