Long-lasting partial regression of glioblastoma multiforme achieved by edotecarin: case report.

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Vrdoljak E, Boban M, Saratlija-Novakovic Z, Jovic J

Long-lasting partial regression of glioblastoma multiforme achieved by edotecarin: case report.

Croat Med J. 2006 Apr;47(2):305-9.

PubMed ID
16625697 [ View in PubMed
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Abstract

We describe the response to a new chemotherapy agent, topoisomerase I inhibitor edotecarin in an 18-year-old woman with recurring glioblastoma. The therapy was administered for 17 months. The radiological partial response and clinical improvement have been achieved, with minor toxicity. Median survival of patients with glioblastoma is 10 months. With edotecarin we have achieved promising result, which should encourage further investigations to develop more efficient therapy for such a deadly disease.

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