Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.

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Clemons WM Jr, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V

Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.

Nature. 1999 Aug 26;400(6747):833-40. doi: 10.1038/23631.

PubMed ID
10476960 [ View in PubMed
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Abstract

The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
30S ribosomal protein S15Q5SJ76Details
30S ribosomal protein S20P80380Details
30S ribosomal protein S4P80373Details
30S ribosomal protein S5Q5SHQ5Details
30S ribosomal protein S6Q5SLP8Details
30S ribosomal protein S7P17291Details
30S ribosomal protein S17P0DOY7Details
30S ribosomal protein S8P0DOY9Details