Pradefovir, a liver-targeted prodrug of adefovir against HBV infection.

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Citation

Tillmann HL

Pradefovir, a liver-targeted prodrug of adefovir against HBV infection.

Curr Opin Investig Drugs. 2007 Aug;8(8):682-90.

PubMed ID
17668370 [ View in PubMed
]
Abstract

Metabasis Therapeutics Inc (previously Ribapharm Inc) is developing pradefovir, an oral liver-targeting prodrug of adefovir developed using its HepDirect technology, for the potential treatment of HBV infection. Phase II clinical trials of pradefovir have been completed.

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