Mogamulizumab: 2 birds, 1 stone.

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Wilcox RA

Mogamulizumab: 2 birds, 1 stone.

Blood. 2015 Mar 19;125(12):1847-8. doi: 10.1182/blood-2015-02-625251.

PubMed ID

25792728 [ View in PubMed

]

Abstract

In this issue of Blood, Duvic et al demonstrate that mogamulizumab, a humanized monoclonal antibody targeting the chemokine receptor CCR4, is well tolerated and has significant clinical activity (overall response rate 36.8%, median duration of response 10.4 months) in heavily pretreated patients with mycosis fungoides (MF) and Sezary syndrome (SS).

DrugBank Data that Cites this Article

Drugs

Mogamulizumab

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Mogamulizumab	C-C chemokine receptor type 4	Protein	Humans	Yes	Antagonist	Details