Isavuconazole treatment of a patient with disseminated mucormycosis.

Article Details

Citation
Copy to clipboard

Peixoto D, Gagne LS, Hammond SP, Gilmore ET, Joyce AC, Soiffer RJ, Marty FM

Isavuconazole treatment of a patient with disseminated mucormycosis.

J Clin Microbiol. 2014 Mar;52(3):1016-9. doi: 10.1128/JCM.03176-13. Epub 2014 Jan 8.

PubMed ID
24403304 [ View in PubMed
]
Abstract

We report a patient with relapsed acute myelogenous leukemia after allogeneic stem cell transplantation who developed disseminated mucormycosis due to Rhizomucor pusillus/R. miehei involving lung, brain, and skin. After failing posaconazole and being intolerant to amphotericin, he was treated effectively with isavuconazole for over 6 months despite ongoing treatment for relapsed leukemia.

DrugBank Data that Cites this Article

Drug Enzymes
DrugEnzymeKindOrganismPharmacological ActionActions
IsavuconazoleCytochrome P450 2C19ProteinHumans
Unknown
Inhibitor
Details