Cloning and sequencing of human LH/hCG receptor cDNA.

Article Details


Minegishi T, Nakamura K, Takakura Y, Miyamoto K, Hasegawa Y, Ibuki Y, Igarashi M, Minegish T [corrected to Minegishi T]

Cloning and sequencing of human LH/hCG receptor cDNA.

Biochem Biophys Res Commun. 1990 Nov 15;172(3):1049-54.

PubMed ID
2244890 [ View in PubMed

We have isolated and sequenced a cDNA encoding the human luteinizing hormone--choriogonadotropin (LH/hCG) receptor. The deduced amino acid sequence (699 residues) containing seven putative transmembrane segments displays sequence similarity to G protein-coupled receptors. The receptor consists of 335 residue extracellular domain which contains six N-linked glycosylation sites. While the protein is 85 and 87% identical overall with the previously cloned rat and porcine LH/hCG receptor respectively, the most highly conserved regions are the putative transmembrane segments (91 and 94% similarity, respectively).

DrugBank Data that Cites this Article

NameUniProt ID
Lutropin-choriogonadotropic hormone receptorP22888Details