Genomic cloning of the human histo-blood group ABO locus.
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Bennett EP, Steffensen R, Clausen H, Weghuis DO, van Kessel AG
Genomic cloning of the human histo-blood group ABO locus.
Biochem Biophys Res Commun. 1995 Jan 5;206(1):318-25.
- PubMed ID
- 7598760 [ View in PubMed]
- Abstract
A P1 phage clone containing the near complete protein coding region of the human histo-blood group ABO gene locus was isolated and characterized. The insert was estimated at approximately 41 kp, and an approximately 20 kbp BamHI fragment contained the near complete coding region as evaluated by Southern blot analysis. Intron/exon boundaries were determined and the coding region was found to span at least seven exons. In situ hybridization to metaphase chromosomes confirmed the predicted localization to 9q34.