Molecular cloning of human GABABR1 and its tissue distribution.
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Makoff A
Molecular cloning of human GABABR1 and its tissue distribution.
Brain Res Mol Brain Res. 1999 Jan 22;64(1):137-40.
- PubMed ID
- 9889352 [ View in PubMed]
- Abstract
GABABR1 clones were isolated from a human cerebellum library. The human sequence is very similar to rat GABABR1 with the cDNAs sharing 91.3% sequence identity and the receptors sharing 98.6% amino acid sequence identity. Northern blotting has shown that the receptor is brain-specific with a widespread distribution throughout the brain but none detected in the spinal cord.