DD genotype of ACE gene is a risk factor for intracerebral hemorrhage.
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Slowik A, Turaj W, Dziedzic T, Haefele A, Pera J, Malecki MT, Glodzik-Sobanska L, Szermer P, Figlewicz DA, Szczudlik A
DD genotype of ACE gene is a risk factor for intracerebral hemorrhage.
Neurology. 2004 Jul 27;63(2):359-61.
- PubMed ID
- 15277638 [ View in PubMed]
- Abstract
Genetic factors may play a role in susceptibility to stroke. The angiotensin converting enzyme (ACE) gene is a candidate gene for two phenotypically different types of stroke affecting small perforating arteries: spontaneous intracerebral hemorrhage (SIH) and ischemic stroke due to small vessel disease (SVD). The authors report evidence that ACE gene DD homozygosity of the I/D polymorphism in intron 16 is an independent risk factor for SIH, and not for SVD stroke, in a Polish population.