Cloning and sequencing of a full length cDNA coding for human retinol-binding protein.
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Colantuoni V, Romano V, Bensi G, Santoro C, Costanzo F, Raugei G, Cortese R
Cloning and sequencing of a full length cDNA coding for human retinol-binding protein.
Nucleic Acids Res. 1983 Nov 25;11(22):7769-76.
- PubMed ID
- 6316270 [ View in PubMed]
- Abstract
We have isolated and sequenced a cDNA clone coding for human Retinol Binding Protein. The sequence indicates that Retinol Binding Protein is synthesized as a single polypeptide chain precursor which is then matured to the secreted protein by removal of a leader peptide. Southern and Northern blot analysis suggest that the gene is present in one or few copies per haploid genome and is transcribed in a single mRNA species.