Primary structure of vitamin K-dependent human protein Z.
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Sejima H, Hayashi T, Deyashiki Y, Nishioka J, Suzuki K
Primary structure of vitamin K-dependent human protein Z.
Biochem Biophys Res Commun. 1990 Sep 14;171(2):661-8.
- PubMed ID
- 2403355 [ View in PubMed]
- Abstract
The primary structure of a vitamin K-dependent human protein Z was determined by a combination of analyses of 41 amino acid residues of the NH2-terminal region and 1265 nucleotide base pairs of a cDNA encoding the residual COOH-terminal part of the protein and the 3' noncoding region. Human protein Z has 360 amino acid residues which is less than that of bovine protein Z containing 396 residues. Human protein Z was composed of an NH2-terminal domain rich in gamma-carboxyglutamic acids, two epidermal growth factor-like domains and a COOH-terminal serine protease-like domain as was bovine protein Z.