Beta-lactam antibiotics: newer formulations and newer agents.

Article Details


Martin SI, Kaye KM

Beta-lactam antibiotics: newer formulations and newer agents.

Infect Dis Clin North Am. 2004 Sep;18(3):603-19, ix.

PubMed ID
15308278 [ View in PubMed

beta-Lactam antibiotics share a common structure and mechanism of action, although they differ in their spectrum of antimicrobial activity and utility in treating different infections. The current classes include the penicillins, the penicillinase-resistant penicillins, the extended- spectrum penicillins, the cephalosporins, the carbapenems, and the monobactams. This article discusses some of the newest beta-lactams available for use in the United States: ertapenem, cefditoren, and cefepime. A new formulation of amoxicillin-clavulanate, which contains higher doses of amoxicillin, is also discussed.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
CefditorenPenicillin-binding protein 1AProteinClostridium perfringens (strain 13 / Type A)