Drotrecogin alfa (activated) approved for treatment of severe sepsis.

Article Details

Citation

Poe K

Drotrecogin alfa (activated) approved for treatment of severe sepsis.

J Am Pharm Assoc (Wash). 2002 May-Jun;42(3):520-2.

PubMed ID
12030642 [ View in PubMed
]
Abstract

Drotrecogin alfa (activated) is a recombinant form of human activated protein C that has been shown to reduce mortality in severely septic patients with a high risk of death. Given the complexity of the inclusion and exclusion criteria, the stability and unique duration of infusion, and the cost of treatment, therapy with this agent should be carefully considered to ensure its appropriate use.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
Drotrecogin alfaCoagulation factor VProteinHumans
Yes
Multitarget
Details