Qutenza(R): a capsaicin 8% patch for the management of postherpetic neuralgia.

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Wallace M, Pappagallo M

Qutenza(R): a capsaicin 8% patch for the management of postherpetic neuralgia.

Expert Rev Neurother. 2011 Jan;11(1):15-27. doi: 10.1586/ern.10.182.

PubMed ID

21158551 [ View in PubMed

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Abstract

Despite currently available treatments, postherpetic neuralgia continues to be a challenging pain condition to treat. Many patients remain in pain or suffer side effects from the (combination) therapies. A patch containing 8% capsaicin (research code NGX-4010 and marketed under the trade name Qutenza((R))), approved both in the EU and USA, provides a localized therapy with effects lasting up to 12 weeks after a single 60-min application. This review will summarize clinical trial evidence on the safety, efficacy and unique attributes of this capsaicin 8% patch in the treatment of postherpetic neuralgia. The action of capsaicin on the transient receptor potential cation channel, subfamily V, member 1 receptors will be discussed.

DrugBank Data that Cites this Article

Drugs

Capsaicin

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Capsaicin	Transient receptor potential cation channel subfamily V member 1	Protein	Humans	Yes	Agonist Regulator	Details