Sequence of the human somatostatin I gene.
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Shen LP, Rutter WJ
Sequence of the human somatostatin I gene.
Science. 1984 Apr 13;224(4645):168-71.
- PubMed ID
- 6142531 [ View in PubMed]
- Abstract
Two human genomic DNA fragments containing alleles for the gene coding for somatostatin I were isolated and sequenced. This gene contains a single intron that interrupts the coding sequence in the propeptide portion of the somatostatin moiety. The site of initiation of transcription of the gene was located by transcription experiments in HeLa cell extracts, and the putative regions for controlling the initiation of transcription were identified.