Specific protein recognition of an mRNA cap through its alkylated base.

Article Details

Citation

Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA

Specific protein recognition of an mRNA cap through its alkylated base.

Nat Struct Biol. 1997 May;4(5):350-4.

PubMed ID
9145102 [ View in PubMed
]
Abstract

The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferaseP07617Details