Pimobendan B from powder diffraction data.

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Zvirgzdins A, Delina M, Mishnev A, Actins A

Pimobendan B from powder diffraction data.

Acta Crystallogr Sect E Struct Rep Online. 2013 Oct 19;69(Pt 11):o1677. doi: 10.1107/S1600536813028353. eCollection 2013 Nov 1.

PubMed ID
24526935 [ View in PubMed
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Abstract

The title mol-ecule, C19H18N4O2 {systematic name: (RS)-6-[2-(4-meth-oxy-phen-yl)-1H-benzimidazol-5-yl]-5-methyl-4,5-di-hydro-pyrida zin-3(2H)-one}, adopts an extended conformation. The dihedral angles between the central benzimidazole ring sytem and the pendant meth-oxy-phenyl and pyridazinone residues are 1.41 (18) and 9.7 (3) degrees , respectively. In the crystal, N-Hcdots, three dots, centeredN hydrogen bonds link the imadazole groups into [001] chains, and pairs of N-Hcdots, three dots, centeredO hydrogen bonds link the pyridazinone groups into dimers. Together, these generate a two-dimensional supra-molecular structure parallel to (010). The layers are linked by C-Hcdots, three dots, centeredpi inter-actions.

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