Tioxidazole: evaluation of antiparasitic activity of a micronized formulation in horses by the critical test method.

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Lyons ET, Drudge JH, Tolliver SC

Tioxidazole: evaluation of antiparasitic activity of a micronized formulation in horses by the critical test method.

Am J Vet Res. 1981 Jun;42(6):1048-9.

PubMed ID
7283235 [ View in PubMed
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Abstract

Antiparasitic activity of a micronized formulation of the benzothiazole compound, tioxidazole, at the dose rate of 11 mg/kg, was evaluated by the critical test method. Drug was given by stomach to 3 horses and on feed to 3 horses. Excellent removal activity was found for Strongylus vulgaris (100%) in 5 naturally infected horses, S edentatus (91% to 100%) in 5 horses, small strongyles (88% to 99%) in 6 horses, immature Oxyuris equi (100%) in 5 horses, and Parascaris equorum (100%) in 5 horses (a 6th horse had 10 small specimens present at necropsy). There was no measurable activity against bots, tapeworms, or stomach worms. Tioxidazole, administered in the feed, was palatable. Signs of toxicosis were not observed.

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