Primary structure of human salivary alpha-amylase gene.
Article Details
- CitationCopy to clipboard
Nishide T, Nakamura Y, Emi M, Yamamoto T, Ogawa M, Mori T, Matsubara K
Primary structure of human salivary alpha-amylase gene.
Gene. 1986;41(2-3):299-304.
- PubMed ID
- 2423416 [ View in PubMed]
- Abstract
A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].