Sequence of the OXA2 beta-lactamase: comparison with other penicillin-reactive enzymes.
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Dale JW, Godwin D, Mossakowska D, Stephenson P, Wall S
Sequence of the OXA2 beta-lactamase: comparison with other penicillin-reactive enzymes.
FEBS Lett. 1985 Oct 21;191(1):39-44.
- PubMed ID
- 3876949 [ View in PubMed]
- Abstract
The nucleotide sequence of the unusual plasmid-mediated OXA2 beta-lactamase is presented, and compared with other beta-lactamases. The OXA2 enzyme has similar features at the presumed active site, but no other significant regions of homology with other penicillin-reactive enzymes. The active site homology may therefore represent convergent evolution of otherwise dissimilar genes.