Hypokalemic periodic paralysis due to the SCN4A R672H mutation in a Turkish family.

Article Details

Citation

Incecik F, Herguner MO, Altunbasak S, Lehman-Horn F

Hypokalemic periodic paralysis due to the SCN4A R672H mutation in a Turkish family.

Turk J Pediatr. 2010 Jul-Aug;52(4):409-10.

PubMed ID
21043388 [ View in PubMed
]
Abstract

Hypokalemic periodic paralysis (HypoPP) is an autosomal dominant disorder characterized by episodic attacks of muscle weakness associated with a decrease in blood potassium levels. Recently, mutations in the gene coding for the skeletal muscle voltage-gated sodium channel alpha subunit (SCN4A) have been reported. We detected the R672H mutation in one HypoPP Turkish family.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Sodium channel protein type 4 subunit alphaP35499Details